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What Are Isotopes?

By the Periodixy Editorial Team · Last reviewed July 11, 2026

Isotopes are versions of the same element that differ only in neutron count. Same protons, same electrons, same chemistry — but different masses, and sometimes very different nuclear stability. Carbon-12 quietly builds your body while carbon-14 slowly decays, letting archaeologists date ancient remains.

An abstract representation of atomic nuclei and isotopes
Photo by Diana ✨ on Pexels

Same element, different mass

The proton count defines the element; the neutron count can vary. Hydrogen has three natural isotopes: protium (0 neutrons), deuterium (1) and tritium (2). All behave chemically as hydrogen because chemistry is run by electrons, and all three have one electron.

IsotopeProtonsNeutronsMass numberNatural share
Carbon-126612≈ 98.9%
Carbon-136713≈ 1.1%
Carbon-146814trace (radioactive)

Notation

Two standard ways to name an isotope: the hyphen form (carbon-14) and the nuclear symbol form, where the mass number rides as a superscript before the symbol: ¹⁴C. The atomic number can be added as a subscript (₆¹⁴C) but is redundant — carbon is always 6.

Why atomic masses are decimals

The periodic table shows a weighted average of natural isotopes. Chlorine (75.8% Cl-35, 24.2% Cl-37) averages to 35.45 amu. Try re-deriving it in the Isotope Abundance Calculator.

Weighted average practice

Boron is 19.9% B-10 (10.013 amu) and 80.1% B-11 (11.009 amu). Find its average atomic mass.

  1. (10.013 × 0.199) + (11.009 × 0.801)
  2. = 1.993 + 8.818

Answer: ≈ 10.81 amu — matching the periodic table.

Stable vs radioactive isotopes

Some neutron–proton combinations are stable forever; others are unstable. A radioactive isotope (or radioisotope) is an isotope whose nucleus is unstable, so it decays over time and emits radiation as it changes into a more stable nucleus. Each radioisotope decays at its own fixed rate, measured by its half-life. Those predictable decay clocks and penetrating radiation give them jobs everywhere:

  • Carbon-14 — dating archaeological remains up to ~50,000 years old.
  • Uranium-238 → lead — dating rocks over billions of years.
  • Technetium-99m — the most common medical imaging isotope.
  • Cobalt-60 — sterilising medical equipment and treating tumours.
  • Americium-241 — the working heart of household smoke detectors.

Summary

  • Isotopes: same protons, different neutrons, same chemistry, different mass.
  • Notation: carbon-14 or ¹⁴C; mass number = protons + neutrons.
  • Periodic table masses are abundance-weighted averages of isotopes.
  • Radioisotopes decay predictably — useful for dating, imaging and treatment.

Frequently asked questions

What is a radioactive isotope?

A radioactive isotope (radioisotope) is an isotope with an unstable nucleus that decays over time, emitting radiation as it turns into a more stable atom. Carbon-14 and uranium-238 are common examples; each decays at a fixed rate set by its half-life.

Do isotopes of an element react differently?

Chemically they react the same way (same electrons). Reaction rates can differ slightly for very light elements — heavy water (D₂O) behaves measurably differently from H₂O.

Are all isotopes radioactive?

No. Most elements have at least one stable isotope. “Isotope” just means a specific neutron count — stability varies case by case.

What is half-life?

The time for half the atoms in a radioactive sample to decay. Carbon-14's half-life of about 5,730 years is what makes radiocarbon dating possible.

Sources & references

  1. Carbon-14: Dating, Mass & Half-life Encyclopædia Britannica
  2. Periodic Table — isotope data Royal Society of Chemistry
  3. Atomic weights and isotopic compositions NIST

Atomic masses and element data follow current IUPAC/NIST standard values. Educational content only — for graded or laboratory work, verify against your course materials. Last reviewed July 11, 2026.

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